Published December 19, 2023 | Version 1.2.0

Exploring combinations of dimensionality reduction, transfer learning, and regularization methods for predicting binary phenotypes with transcriptomic data

  • 1. Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

Description

This repository contains supplementary materials for the research paper "Exploring combinations of dimensionality reduction, transfer learning, and regularization methods for predicting binary phenotypes with transcriptomic data." The materials are organized into two distinct folders:

- supplementary_code: source code to reproduce the analysis
    AE network training
    AVAE network training
    phenotype data collection
    predictive modeling pipeline

- supplementary_data: networks and datasets used in this study
    01: trained AE network
    02: trained AVAE network
    03: trained c-ICA network
    04: 30 transcriptomic datasets with all representations and phenotypes
    05: dataset predictive performances and significance
    06: robustness analysis
   

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