Published December 14, 2023 | Version v1
Dataset Open

Atrophy Pattern Maps of Frontotemporal Dementia variants (bvFTD, svPPA, pnfaPPA)

  • 1. McGill University

Description

The files contain voxel-wise t-statistics maps contrasting deformation based morphometry (DBM) measurements of frontotemporal dementia (FTD) patients, divided according to subtype diagnosis, against matched normal controls.

BV = behavioral-variant Frontotemporal Dementia

SV = semantic-variant Primary Progressive Aphasia

PNFA = non-fluent-variant Primary Progressive Aphasia

 

FTD map is based on NIFD data, available at: https://memory.ucsf.edu/research/studies/nifd

For more information regarding the participants and method details, see:

Dadar, Mahsa, et al. "White matter hyperintensities are associated with grey matter atrophy and cognitive decline in Alzheimer's disease and frontotemporal dementia." Neurobiology of aging 111 (2022): 54-63.

Metz, Amelie, et al. "Brain Atrophy and White Matter Hyperintensities in Frontotemporal Dementia Variants and their Impact on Cognition" [Conference presentation] CCNA 2024 Partners Forum and Science Days (2024, March 19-21).

Files

Files (173.7 MB)

Name Size Download all
md5:e7da438ef51a3a41a329e7421365dade
7.1 MB Download
md5:95a7b7aeced5887154a6cb3f7f500e59
34.1 MB Download
md5:a96c11f12f93ae5d7d5626f76e8fa245
15.8 MB Download
md5:70161410e1a71581891ef3c373d68ae4
34.1 MB Download
md5:bf412dcf16685231532ef2fde8b771f6
7.2 MB Download
md5:e057bf0aaa574d16d36de140f25ae282
34.1 MB Download
md5:62eb7924bc6d4fd679250e5781ff57ee
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md5:41af1d99282035275ff675eb4405a1b8
34.1 MB Download

Additional details

References

  • Dadar, Mahsa, et al. "White matter hyperintensities are associated with grey matter atrophy and cognitive decline in Alzheimer's disease and frontotemporal dementia." Neurobiology of aging 111 (2022): 54-63.
  • Metz, Amelie, et al. "Brain Atrophy and White Matter Hyperintensities in Frontotemporal Dementia Variants and their Impact on Cognition" [Conference presentation] CCNA 2024 Partners Forum and Science Days (2024, March 19-21).