Published December 14, 2023 | Version v2
Software Open

Electronic Notebooks: pH-sensitive coarse-grained model of mRNA lipid nanoparticles

Authors/Creators

  • 1. Structural Biology and NMR Laboratory and The Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark
  • 2. The Hartree Centre, Science and Technology Facilities Council (STFC) Daresbury Laboratory, Warrington, WA4 4AD, United Kingdom
  • 3. Division of Computational Chemistry, Department of Chemistry, Lund University, Lund SE-221 00, Sweden
  • 4. Advanced Drug Delivery, Pharmaceutical Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Mölndal 431 83, Sweden

Description

This repository contains electronic notebooks (Jupyter) for reproducing the simulation results presented in the scientific paper Lipid shape and packing are key for optimal design of pH-sensitive mRNA lipid nanoparticles

Files

gitesei/SI-LNPs-v2.zip

Files (142.8 MB)

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Additional details

Related works

Is supplement to
https://github.com/gitesei/SI-LNPs (URL)
10.1073/pnas.2311700120 (DOI)