Winnie09/GPTCelltype: v1.0.1

Cell type annotation is an essential step in single-cell RNA-seq analysis. However, it is a time-consuming process that often requires expertise in collecting canonical marker genes and manually annotating cell types. Automated cell type annotation methods typically require the acquisition of high-quality reference datasets and the development of additional pipelines. We demonstrated that GPT-4, a highly potent large language model, can automatically and accurately annotate cell types by utilizing marker gene information generated from standard single-cell RNA-seq analysis pipelines in this manuscript. We developed this software, GPTCelltype, to provide reference-free, cost-effective automated cell type annotation using GPT-4 for single-cell RNA-seq analysis.