Published October 17, 2023 | Version v1
Dataset Open

Community Package VanGalen-Oetjen Dataset

  • 1. ROR icon Ludwig-Maximilians-Universität München
  • 2. ROR icon Helmholtz Zentrum München

Description

The Community package (https://github.com/SoloveyMaria/community) is an R package designed for the analysis of single-cell RNA sequencing data, specifically for inferring interactions between different cell types. The dataset provided here is compatible with the Community tool, allowing for direct utilization. 

Both datasets VanGalen (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE116256) and Oetjen (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE120221) have undergone peer review and has ben published.  It's important to note that the data in this repository has undergone batch correction and normalization, and the corresponding metadata has been appropriately adjusted (for detailed insights into the preprocessing steps, you can review the information provided at our paper repository: preprocessing). This processed data serves as the input for the Community tool.

Files

anno_cells_corr.txt

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Additional details

Dates

Other
2023-10

References

  • Van Galen, P., et al. (2019). Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. Cell
  • Oetjen, KA., et al. (2018). Human bone marrow assessment by single-cell RNA sequencing, mass cytometry, and flow cytometry. JCI Insight