Published January 1, 2009
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Synthetic studies on vincorine: access to the 3a,8a-dialkyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole skeleton
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Synthetic studies on vincorine are described; the conversion of
3-aminoethyl-3-alkyloxindoles to 3a,8a-dialkyl-1,2,3,3a,8,8ahexahydropyrrolo[
2,3-b]indoles has been achieved through an
addition–cyclization sequence, and a fully functionalized key
intermediate was constructed with this method.
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