Journal article Open Access

The cell biology of mammalian fertilization

Okabe, Masaru

Fertilization is the process by which eggs and spermatozoa interact, achieve mutual recognition, and fuse to create a zygote, which then develops to form a new individual, thus allowing for the continuity of a species. Despite numerous studies on mammalian fertilization, the molecular mechanisms underpinning the fertilization event remain largely unknown. However, as I summarize here, recent work using both gene-manipulated animals and in vitro studies has begun to elucidate essential sperm and egg molecules and to establish predictive models of successful fertilization.
Files (3.8 MB)
Name Size
article.pdf
md5:ceddbaf2aba88555f5cee6f0ef142a63
3.8 MB Download
294
213
views
downloads
Views 294
Downloads 213
Data volume 801.7 MB
Unique views 273
Unique downloads 196

Share

Cite as