Published January 1, 2008 | Version v1
Journal article Open

Persistent use of "false" cell lines

Creators

Description

From HeLa and its multiple identities, to MDA-MB-435, erroneously and widely used as breast cancer cells, the history of cancer cell lines is rich in misidentification and cross-contamination events. Despite the fact that these problems were regularly signaled during the last decades, many actors of research still seem to ignore them. A never-ending story? Solutions exist, notably based on recent technical advances in cell line authentication (short tandem repeat analysis). However, a collaborative action involving users of cell lines, cell banks, journals and funding agencies is needed to achieve success.

Files

article.pdf

Files (66.7 kB)

Name Size Download all
md5:4c88a47f9d0ce0bea2584207408a4ac3
66.7 kB Preview Download