The ancient guardian: ZAR1 evolutionary journey and adaptations
Authors/Creators
- 1. Kyoto University
- 2. The Sainsbury Laboratory
Description
Read it on Medium (recommended).
Imagine a plant immune system that has been protecting plants since the time of dinosaurs. Sounds fascinating, right? Well, that’s exactly what we discovered about a plant immune receptor called ZAR1. In our recent study, we delved into the evolutionary history of ZAR1 and uncovered some intriguing findings.
Read the paper: Hiroaki Adachi, Toshiyuki Sakai, Jiorgos Kourelis, Hsuan Pai, Jose L Gonzalez Hernandez, Yoshinori Utsumi, Motoaki Seki, Abbas Maqbool, Sophien Kamoun, Jurassic NLR: Conserved and dynamic evolutionary features of the atypically ancient immune receptor ZAR1, The Plant Cell, Volume 35, 3662–3685.
Read the commentary: Ching Chan, Tracing the evolution of the ZAR1 resistosome back to the Jurassic era, The Plant Cell, Volume 35, 3629–3630.
More on EVO-MPMI: Schornack, Sebastian and Kamoun, Sophien. (2023). EVO-MPMI: From fundamental science to practical applications. Zenodo https://doi.org/10.5281/zenodo.8030196
Files
JurassicNLR.pdf
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Additional details
Funding
- UK Research and Innovation
- Mechanisms of pathogen suppression of NLR-mediated immunity BB/V002937/1
- UK Research and Innovation
- Genome evolution of a pandemic clonal lineage of the wheat blast fungus BB/W008157/1
- UK Research and Innovation
- Recognition BBS/E/J/000PR9795
- UK Research and Innovation
- Engineering CC-HMA-NLR immune receptors for disease resistance in crops (ERiC) BB/W002221/1
- UK Research and Innovation
- Susceptibility BBS/E/J/000PR9797
- European Commission
- BLASTOFF - Retooling plant immunity for resistance to blast fungi 743165
- UK Research and Innovation
- Evolution BBS/E/J/000PR9798