Published September 19, 2023 | Version v1

MICROBIOLOGICAL CHARACTERISTICS OF THE DISEASE IN PATIENTS WITH CHRONIC PURULENT OTITIS MEDIA - URGENCH BRANCH OF TASHKENT MEDICAL ACADEMY

  • 1. Head of Department Otorрhinolaryngology and Ophthalmology, Al-Khorazmiy St 28, Urgench City, Uzbekistan.
  • 2. PhD, Assistant, Department of Microbiology, Al-Khorazmiy St 28, Urgench City, Uzbekistan.
  • 3. Assistant, Department of Otorрhinolaryngology and Ophthalmology, Al-Khorazmiy St 28, Urgench City, Uzbekistan.
  • 4. Student, Urgench Branch of the Tashkent Medical Academy, Al-Khorazmiy St 28, Urgench City, Uzbekistan
  • 5. PhD, Assistant, Tashkent Medical Academy, Farobiy st 2, Tashkent city, Uzbekistan.

Description

Abstract

The main goal of the research was to analyze the etiological and pathogenetic characteristics of the disease and to evaluate and scientifically substantiate the main factors of the type of microbe, growth pattern, environmental resistance in the development of the disease. According to our data, polyresistant strains of S.aureus and Ps.aeruginosa are the main cause of inflammation in the middle ear cavities. The microorganisms that grew at the highest level were S. aureus 59.3%, 45.1% and 49.7% in all three groups, S. epidermidis 16.3%, 38.2% and 32.1% respectively, and Ps.aeruginosa was observed in 24.1%, 16.7% and 18.2% of strains. In the obtained results, it was clearly determined that the incidence of Pseudomonas aeruginosa was 46.6% in mesotympanitis and 79.7% in epitympanitis. The same situation was observed in Staphylococcus aureus , in which it was 43.9% in mesotympanitis and 55.3% in epitympanitis. According to the results of determining the sensitivity of microbes to antibiotics, the change of P.aeruginosa strain isolation (IPM_10IU) 59.0%, to meropenem (MEM_10 IU) 71.0%, to ceftazidime (CAZ_10 IU) 69.0%, to amikacin (AMK-30 IU) 46.0%, to ciprofloxacin. (CIP-5 IU) was 78.0% and levofloxacin (LVX-5 IU) - 77.0%.

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