Mathematical Model of IL-1- NF kB Biological Module

ABSTRACT:

In this paper we develop mathematical model of IL − 1 — NF κB signaling pathway. First, we describe physiology and draw functional diagram, then, based on physiology, we state set of biochemical reactions to describe underlying biochemistry. At last we develop mathematical model. Parameter data are chosen from experimental literature or are assumed (for IL − 1). For plausable set of parameter data we run simulations.