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Published October 10, 2023 | Version v1
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Vaccination of poultry against highly pathogenic avian influenza – part 1. Available vaccines and vaccination strategies. Annex A–Supplementary information on ToR 1 data

Authors/Creators

  • 1. European Food Safety Authority
  • 2. European Union Reference Laboratory for Avian Influenza
  • 3. University of Copenhagen, Denmark
  • 4. Universidad Complutense de Madrid, Spain
  • 5. : Institut d'Enseignement Supérieur et de recherche en Alimentation, Santé Animale, Sciences Agronomiques et de l'Environnement, Lyon
  • 6. Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G.Caporale"
  • 7. Università degli Studi di Milano, Italy
  • 8. Royal Veterinary College, UK
  • 9. Assistance Publique - Hôpitaux de Paris / Université Paris Est Créteil, France
  • 10. Wageningen Bioverterinary Research, The Netherlands
  • 11. Universidad de Castilla - La Mancha, Spain
  • 12. Aarhus University, Denmark
  • 13. Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail, France
  • 14. Universitat de les Illes Balears, Spain
  • 15. Università di Bologna, Italy
  • 16. Department of the Environment, Food and Rural Affairs, UK
  • 17. Wageningen Livestock Research, The Netherlands
  • 18. National Veterinary Institute, Sweeden
  • 19. Institut de Recerca i Tecnologia Agroalimentàries, Spain
  • 20. University of Natural Resources and Life Sciences (BOKU), Austria
  • 21. European Medicines Agency, The Netherlands
  • 22. Istituto Zooprofilattico Sperimentale delle Venezie, Italy
  • 23. INRAE (French national research institute for agriculture, food and environment), France
  • 24. Friedrich-Loeffler-Institut, Germany
  • 25. Utrecht University, The Netherlands
  • 26. European Food Safety Authority, Italy
  • 27. Estonian University of Life Sciences, Estonia

Description

Table A.1 - Available vaccines for HPAI in poultry. The table includes information on vaccine characteristics such as HA seed strain, vaccine dosage and administration route, target species, authorisation status, challenge strain, duration of immunity and source of information.

Table A.2 - Challenge experiments. The table includes data extracted from 28 selected studies from literature on challenge experiments. The data was used to quantify VES, VEm, VEsh and VEs,sh for each vaccine assessed within each study. For each value of VEs,sh the probability Rvac < 1 was estimated to infer the probability of the vaccine to potentially stop transmission in vaccinated birds (VET).

Table A.3 - Transmission experiments. The table includes data extracted from 12 studies from the literature, data was used from the unvaccinated and vaccinated groups to quantify VES, VEm, VEsh and VEs,sh for each vaccine assessed within each study; the estimated R values for the unvaccinated (Runv) and vaccinated (Rvac) groups were also extracted. The Rvac values were used to create a binomial variable classifying whether the vaccine could stop transmission (R < 1) or not.

Notes

EU; XLSX; ahaw@efsa.europa.eu

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Additional details

Related works

Is supplement to
Journal article: 10.2903/j.efsa.2023.8271 (DOI)

Subjects

avian influenza
http://id.agrisemantics.org/gacs/C9971
vaccine
http://id.agrisemantics.org/gacs/C962
poultry
http://id.agrisemantics.org/gacs/C227