IMI ConcePTION
Published August 2, 2023 | Version v1
Project deliverable Open

Generic PBPK template for predicting drug concentration time profiles in human breast milk (D3.6)

Description

This deliverable described in the present report reports on the development, evaluation and application of a generic Physiologically-based pharmacokinetic modelling (PBPK) template:

  • To predict medicine concentration time profiles in human milk;
  • To calculate milk-associated medicine doses ingested by neonates and infants.

Files

821520_ConcePTION_D3.6_Generic PBPK template for predicting drug concentration time profiles in human breast milk.pdf

Files (3.1 MB)

Additional details

Funding

European Commission
ConcePTION - Building an ecosystem for better monitoring and communicating of medication safety in pregnancy and breastfeeding: validated and regulatory endorsed workflows for fast, optimised evidence generation 821520