Published April 20, 2015 | Version pdf
Journal article Open

Study Of GABA Metabolism In The Mitochondrial Fraction orThe Brain Cells Of Rats After A Single Administration Of Thymalinum

Creators

  • 1. Institute of Physiology named after A.I. Garayev, ANAS

Description

It was established that after intramuscular administration of thymalinum the activity of glutamate
decatboxylase increased and activity of GABA-aminotransferase lowered in mitochondria of the brain ceils
Thus, contents of glhutamic and aspartic acids decreased, while gamma-aminobutyric acid increased in the
mitochondria of the hypothalamus, cerebellum, visual and motor cortex. Changes in the metabolism of
GABA fter the thymalinum action occurred due to the interaction between nervous and immune systems

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