Green Synthesis of Zinc Oxide (ZnO) Nanoparticles Using Aqueous Extract of Shilajit: Their Characterization and Anticancer Activity
- Parthasarathi Perumal1
- Nazeer Ahamed Sathakkathulla1
- Kalaivani Kumaran2
- Ramaladevi Ravikumar2
- Justin Jayaraj Selvaraj2
- Vijayakumar Nagendran2
- Mariappan Gurusamy3
- Naazneen Shaik3
- Senthilkumar Gnanavadivel Prabhakaran4
- Vinothkumar Suruli Palanichamy5
- Vellaichamy Ganesan5
- Purushoth Prabhu Thiraviam6
- Seshan Gunalan7
- Suresh Rathinasamy1
- 1. Department of Molecular and Cell Biology Lab, Greensmed Labs, Thoraipakkam, Chennai - 600097, India
- 2. Department of Pharmaceutical chemistry, EGS Pillay College of Pharmacy, Nagapattinam - 611002, India
- 3. Department of Pharmaceutics, St. Mary's College of Pharmacy, Secunderabad, Telangana - 500025, India
- 4. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Bharath Institute of Higher Education and Research (BIHER), Chennai - 600044, India
- 5. Department of Pharmaceutical Chemistry, Pannai College of Pharmacy (Affiliated to The Tamil Nadu Dr. M.G.R. Medical University, Chennai), Dindigul - 624005, India
- 6. Department of Pharmacognosy, C. L. Baid Metha College of Pharmacy, Chennai - 600096, India
- 7. Centre of Advanced Study in Crystallography and Biophysics, Guindy Campus, University of Madras, Chennai - 600025, India
Description
UV analysis of aqueous extract of shilajit and zinc oxide nanoparticles (ZnO NPs) of shilajit extract showed the absorbance peaks at 422.40 nm and 357.90 nm. The abosrbance peaks confirms the presence of ZnO NPs in the reaction mixture.
The FTIR spectrum of shilajit extract and ZnO NPs of shilajith extract showed the strong broad absorbance at 3428 cm−1 are due to the stretching vibration of hydroxyl (OH) functional groups. The absorption band at 1633 cm-1 corresponded the stretching vibration of N-H groups. The peak at 1414 cm-1 observed in the spectrum indicate the presence of mono-substituted alkynes. The peak at 1163 cm-1 showed the presence of C-O bonds.
The XRD pattern of ZnO NPs of shilajith extract, characterized by their high intensity, were observed at specific 2θ peak values, namely 31.69°, 34.33°, 36.17°, 47.45°, 56.52°, 62.77°, 67.87° and 68.99°, and can be attributed to the lattice planes (100), (002), (101), (102), (110), (103), (112), and (201), respectively.
The particle size of ZnO NPs of shilajit extract was measured to be 348 nm and the polydispersity index was found to be 0.322.
Files
Characterization_data.zip
Files
(633.6 kB)
| Name | Size | Download all |
|---|---|---|
|
md5:3ad79c37263ed09675285eedddce026e
|
633.6 kB | Preview Download |