3D Printing of Personalised Carvedilol Tablets Using Selective Laser Sintering - Underlying Data
- 1. μ-VIS X-ray Imaging Centre, Faculty of Engineering and Physical Sciences, University of Southampton, Southampton, United Kingdom, SO17 1BJ, UK
- 2. CRI Centre for Research Innovation, University of Greenwich, Chatham ME4 4TB, UK; Delta Pharmaceutics Ltd., Chatham, Kent ME4 4TB, UK
- 3. Institute of Technology in Measurements and Instrumentation, University of Rouen, 76130 Mont Saint Aignan, France
- 4. The Wolfson Centre for Bulk Solids Handling Technology, Faculty of Engineering and Science University of Greenwich, Chatham ME4 4TB, UK
- 5. Drug Product Development, Bristol Myers Squibb, 556 Morris Avenue, Summit, NJ 07901, USA
- 6. Bristol Myers Squibb, Reeds Lane, Moreton, Wirral CH46 1QW, UK
Description
Underlying μCT Data for "3D Printing of Personalised Carvedilol Tablets Using Selective Laser Sintering"
by Atabak Ghanizadeh Tabriz, Quentin Gonot-Munck, Arnaud Baudoux, Vivek Garg, Richard Farnish, Orestis L. Katsamenis, Ho-Wah Hui, Nathan Boersen, Sandra Roberts, John Jones, and Dennis Douroumis
published in MDPI pharmaceutics
In section: Physical Pharmacy and Formulation, Recent Non-oral Dosage Form Development: Focus on 3D-Printed Formulations
The micro- and macro-porosities of representative 3D-printed tablets at 25%, 40%, and 55% laser intensities was measured. SLS-printed components were also characterised by means of X-ray microfocus computed tomography (μCT). Imaging was performed at the University of Southampton’s μ-VIS X-ray Imaging Centre (www.muvis.org) using a customised μCT scanner optimised for 3D X-ray histology (www.xrayhistology.org). The system, which is based on Nikon’s XTH225ST system (Nikon Metrology UK Ltd.)
Data index
- 20230206_XRH_3299_OLK_PHAR08603-DOSF_40.zip
- Dataset (including ORS Dragonfly analysis file) of object printed at 40% laser power
10 µm voxel size isotropic
- Dataset (including ORS Dragonfly analysis file) of object printed at 40% laser power
- 20230206_XRH_3299_OLK_PHAR08616-DOSF.zip
- Dataset (including ORS Dragonfly analysis file) of object printed at 55% laser power
10 µm voxel size isotropic
- Dataset (including ORS Dragonfly analysis file) of object printed at 55% laser power
- 20230206_XRH_3299_OLK_PHAR08616-DOSF_25.zip
- Dataset (including ORS Dragonfly analysis file) of object printed at 25% laser power
10 µm voxel size isotropic
- Dataset (including ORS Dragonfly analysis file) of object printed at 25% laser power
- SLS-3DP_OLK-CorrectRes.xlsx
- Analysis results & graphs
X-ray CT analysis conducted using Dragonfly software (v. 2022.1.0.1231; Object Research Systems (ORS) Inc, Montreal, Canada, 2020; software available at http://www.theobjects.com/dragonfly