Morphological Spectrum of Endometrium in Patients Presenting with Dysfunctional Uterine Bleeding
Authors/Creators
- 1. Department of Pathology, Subharti Medical College, Subharti Puram, Meerut - 250005 (U.P.)
Description
Dysfunctional uterine bleeding (DUB) is a clinical term used to describe bleeding not attributable to any underlying organic pathological condition. A total of 187 patients were included in the present study which were categorized in reproductive (50yrs) age groups. One hundred sixteen cases (62%) were in reproductive age group, 47 cases (25.1%) in perimenopausal age group and 24 cases (12.8%) in postmenopausal age group. Histopathological examination of dilatation and curettage (D&C) samples was done to elucidate the cause of DUB. In reproductive age group, proliferative endometrium was the most common finding (26.8%) followed by irregular maturation (25%).Complex hyperplasia was seen in 6 cases, out of which 1 case showed atypia. Nineteen cases (16.4%) showed associated endometritis. No case of malignancy was observed in this group. In perimenopausal age group, simple hyperplasia was the most frequent finding (29.8%).Complex hyperplasia was seen in 3 cases, out of which 1 revealed atypia. Three cases of malignancy (6.4%) were reported. In postmenopausal age group, most frequent finding in DUB was complex hyperplasia seen in 8 cases (33.3%), out of which 2 cases showed atypia. Six cases (25%) of simple hyperplasia and 4 cases (16.7%) of malignancy were reported. Atrophic endometrium was observed in D&C samples from 6 patients (25%).
Files
4. A. Khare.pdf
Files
(120.3 kB)
| Name | Size | Download all |
|---|---|---|
|
md5:c10a72b329ca4aaca31e7dca988d60a7
|
120.3 kB | Preview Download |
Additional details
References
- 1. Abdullah LS, Bondagji NS: Histopathological Pattern of Endometrial Sampling Performed for Abnormal Uterine Bleeding. Bahrain Medical Bulletin, 2011;33(4):1-6.
- 2. ACOG Practice Bulletin: Management of Anovulatory Bleeding. International Journal Gynaecology & Obstetrics, 2001;72(3):263-271
- 3. Awwad JT, Toth TL, Schiff I: Abnormal Uterine Bleeding in the Perimenopause. International Journal of Fertility & Menopausal Studies, 1993;38(5):261-269.
- 4. Baral R, Pudasaini S: Histopathological pattern of endometrial samples in abnormal uterine bleeding. Journal of Pathology of Nepal, 2011;1:13-16.
- 5. Crum CP: The female genital tract. In: Robbins & Cotran: Pathological basis of disease. V Kumar, AK Abbas, N Fausto (Eds.); 8th Edn.; Saunders: An imprint of Elsevier, Philadelphia, 2010;pp.1026-1027.
- 6. Dangal G: A study of endometrium in patients with abnormal uterine bleeding at Chitwan valley . Kathmandu University Medical Journal, 2003;1(2):110- 112.
- 7. Deligdisch L: Hormonal Pathology of the Endometrium. Modern Pathology, 2000;13(3):285–294
- 8. Gredmark T, Kvint S, Havel G, Mattsson LA: Histopathological findings in women with post menopausal bleeding. British Journal of Obstetrics and Gynecology, 1995;102(2):133-136.
- 9. Mutter GL, Ferenczy A: Anatomy and histology of the uterine corpus. In: Blaustein's pathology of the female genital tract. RJ Kurman (Ed.); 5th Edn.; Springer (India) New Delhi, 2004;pp.383-419.
- 10. Muzaffar M, Akhtar KA, Yasmeen S, Rehman MU, Iqbal W, Khan MA: Menstural irregularities with excessive blood loss:a clinic-pathological correlation. The Journal of Pakistan Medical Association, 2005;55(11):486-489.
- 11. Prat J: Female reproductive system. In: Anderson's Pathology.; I Damjanov , J Linder (Eds.); 10th Edn.; Vol. II. Elsevier, Philadelphia, 2009;pp.2231-2309.
- 12. Rosai J: Female reproductive system-uterus-corpus. In: Rosai and Ackerman's Surgical Pathology. 9th Edn.; Mosby: An Imprint of Elsevier, Missouri, 2005;pp.1579- 1615.
- 13. Sherman ME, Mazur MT, Kumart RJ: Benign diseases of the endometrium. In: Blaustein's pathology of the female genital tract. RJ Kurman (Ed.); 5th Edn.; Springer (Indian) New Delhi, 2004;pp.421-466.
- 14. Wren BG: Dysfunctional Uterine Bleeding. Australian Family Physician, 1998; 27(5):371-377.