Published June 30, 2021
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Alkaloids bearing rare skeletons from Forsythia suspensa with anti-inflammatory and anti-viral activities in vitro
Authors/Creators
- 1. * & School of Pharmaceutical Science, Yantai University, Yantai, 264005, People's Republic of China
Description
Zhao, Lin, Li, Wei, Dai, Sheng-Jun, Liu, Rong-Xia, Xie, Ze-Ping, Zhang, Shu-Min, Yue, Xi-Dian (2021): Alkaloids bearing rare skeletons from Forsythia suspensa with anti-inflammatory and anti-viral activities in vitro. Phytochemistry (112739) 186: 1-7, DOI: 10.1016/j.phytochem.2021.112739, URL: http://dx.doi.org/10.1016/j.phytochem.2021.112739
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- urn:lsid:plazi.org:pub:FFEBFFEDD415FFAFFFBBFFBCFFA5A00E
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- In vitro, compounds 1-5 were evaluated for their anti-viral activities against the H1N1 virus. Five alkaloids showed activities; their IC50 values are shown in Table 3. In addition, the anti-viral activities against the RSV of five alkaloids were also tested. As a result, these alkaloids showed activities, as shown in Table 3. The first isolated five alkaloids showed better anti-viral activities against the H1N1 virus and RSV compared with the previously isolated labdane diterpenoids from this plant (Zhao et al., 2020).