Etiological Factors, Clinico-Hematological Profile and Severity of Anaemia: A Hospital Based Study
Authors/Creators
- 1. Department of Internal Medicine, People's College of Medical Sciences and Research Centre, Bhopal
Description
This hospital based cross-sectional study was undertaken to assess etiological factors, clinico-hematological profile
and severity of anaemia among patients above 18 years of age in a tertiary care hospital in Bhopal. Consecutive patients
diagnosed with anemia based on WHO classification were recruited from out patients and from admitted patients in wards of
Department of Medicine, PCMS, Bhopal. A total of 142 patients aged between 18-83 years were recruited in the study. The
mean age of the participants was 31.8 years and majority (64%) were females. The commonestpresenting clinical feature
was pallor (68%). The mean hemoglobin among the participants was 7.2 gm/dl. The mean MCV, MCH and MCHC were
72.7 fl, 24.8 pg and 27.3 gm/dl, respectively. Most(60%) patients had a peripheral smear picture of microcytic hypochromic
anemia. The etiology was: iron deficiency anemia 75%, anemia with chronic diseases 14%, hemolytic anemia 4%,anemia
associated with acute illness 4%. Pancytopenia was diagnosed in 11% and megaloblastic anemia in 5%. Severe anemia was
diagnosed in 59% of patients. Iron deficiency is the most common cause of anemia in thestudy. Females are at more risk for
severe anemia. Prevention and intervention programs for severe anemia are required with main focus on females.
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Additional details
References
- 1. Cappellini MD, Motta I. Anemia in Clinical Practice- Definition and Classification: Does Hemoglobin Change With Aging? Semin Hematol. 2015;52(4):261- 9. 2. WHO | The global prevalence of anaemia in 2011. WHO [Internet]. 2015 [cited 2018 Aug 22]; Available f r o m : h t t p : / / w w w . w h o . i n t / n u t r i t i o n / publications/micronutrients/global_ prevalence _anaemia_2011/en. 3. Alem M, Enawgaw B, Gelaw A, Kenaw T, Seid M, Olkeba Y. Prevalence of Anemia and Associated Risk Factors among Pregnant Women Attending Antenatal Care in Azezo Health Center Gondar Town, Northwest Ethiopia. J Interdiscip Histopathol. 2013;1(3):137. 4. Balarajan Y, Ramakrishnan U, Özaltin E, Shankar AH, Subramanian S. Anaemia in low-income and middle- income countries. Lancet. 2011;378-(9809):2123–35. 5. Adamu AL, Crampin A, Kayuni N, Amberbir A, Koole O, Phiri A, et al. Prevalence and risk factors for anemia severity and type in Malawian men and women: urban a n d r u r a l d i ff e r e n c e s . P o p u l H e a l t h M e t r. 2017;15(1):12. 6. Kassebaum NJ, Jasrasaria R, Naghavi M, Wulf SK, Johns N, Lozano R, et al. A systematic analysis of global anemia burden from 1990 to 2010. Blood. 2014;123(5):615–24. 7. Tolentino K, Friedman JF. An update on anemia in less developed countries. Am J Trop Med Hyg. 2007;77(1):44–51. 8. van den Broek N. Anaemia and micronutrient deficiencies. Br Med Bull. 2003;67:149-60. 9. WHO | Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. WHO [Internet]. 2014 [cited 2018 Aug 22]; Available from: http://www.who. int/vmnis/indicators/ haemog- lobin/en. 10. Sadeghian M, Fatourechi A, Lesanpezeshki M, Ahmadnezhad E. Prevalence of anemia and correlated factors in the reproductive age women in rural areas of tabas. J Fam Reprod Heal. 2013;7(3):139-44. 11. Roy CN. Anemia of Inflammation. Hematology. 2010;(1):276–80. 12. Weiss G. Pathogenesis and treatment of anaemia of chronic disease. Blood Rev. 2002;16(2):87–96. 13. Kalantri A, Karambelkar M, Joshi R, Kalantri S, Jajoo U. Accuracy and reliability of pallor for detecting anaemia: a hospital-based diagnostic accuracy study. PLoS One. 2010;5(1):e8545. 14. Ratre B, Ratre BK, Patel NP, Patel U, Jain R, Sharma VK. Clinical and Epidemiological profile of Anemia in central India. Int J Med Res Rev. 2014;2(01).