People's Journal of Scientific Research
Published June 1, 2017 | Version v1
Journal article Open

Role of Honey in Post tonsillectomy Pain: A Randomized Double Blind Study

Authors/Creators

  • 1. Consultant ENT, Department of Surgery, College of Medicine, King Khalid University, Abha, P.O. Box 641, Kingdom of Saudi Arabia.
  • 2. Department of Family and Community Medicine, College of Medicine, King Khalid University, Abha, P.O. Box 641, Kingdom of Saudi Arabia.

Description

Tonsillectomy is one of the most commonly performed surgical procedures among pediatric age group. Administration of honey in post-operative cases of tonsillectomy can reduce the need of painkillers by significantly reliving of pain in children. A randomized double blind control study design conducted among 110 patients, randomly divided in two equal groups, with the aim to evaluate the effect of using honey on post tonsillectomy pain along with paracetamol among children. First group was given paracetamol and honey, whereas second group was treated with paracetamol and placebo. Standardized general anesthesia, post surgery analgesics and antibiotics were administered to all the patients. Data were gathered by using visual analogue scale (VAS) and entered in SPSS then analyzed. A significant difference between paracetamol plus honey and paracetamol plus placebo for both visual analogue scale (VAS). Number of painkillers taken with in 5 days post-operatively were significantly different (p<0.01).The results also reveal that the consumption of paracetamol who received honey was lower than control group. After tonsillectomy, oral administration of honey has effective role in pain management and can reduce the dose of painkillers post-operative surgery among children.

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References

  • 1. Rony RYZ, Fortier MA, Chorney JM, Perret D, Kain ZN. Parental postoperative pain management: attitudes, assessment, and management. Pediatrics 2010;125:e1372-1378.
  • 2. Windfuhr JP. Serious Complications following Tonsillectomy: How Frequent Are They Really? ORL 2013;75:166-173.
  • 3. Ahmadi N. Children are Different from Adults. 2013. http://www.drnavident.com. Retrieved 25.01.2017
  • 4. Moir MS, Bair E, Shinnick P, Messner A. Acetaminophen versus acetaminophen with codeine after pediatric tonsillectomy. Wiley Online Library. 2000. pp. 1824–1827.
  • 5. Bartley JR, Connew AM. Parental attitudes and postoperative problems related to paediatric day stay tonsillectomy. New Zealand Med J. 1994;107 (989):451.
  • 6. Mansour AM, Zein W, Haddad R, Khoury J. Bullous keratopathy treated with honey. Wiley Online Library; 2004. pp. 312–313.
  • 7. Ozlugedik S, Genc S, Unal A, Elhan AH, Tezer M, Titiz A. Can postoperative pains following tonsillectomy be relieved by honey?: A prospective, randomized, placebo controlled preliminary study. Int J Pediatotorhinolaryngol. 2006; 70(11):1929-1934
  • 8. Khan FR, Abadin ZU, Rauf N. Honey: nutritional and medicinal value. Int J Clin Pract. 2007; 61(10):1705–1707.
  • 9. Misirlioglu A, Eroglu S, Karacaoglan N, Akan M, Akoz T, Yildirim S. Use of Honey as an Adjunct in the Healing of Split Thickness Skin Graft Donor Site. Wiley Online Library; 2003. pp. 168–172.
  • 10. Subrahmanyam M. Topical application of honey in treatment of burns. Wiley Online Library; 1991. pp. 497–498.
  • 11. Swellam T, Miyanaga N, Onozawa M, Hattori K, Kawai K, Shimazui T, et al. Antineoplastic activity of honey in an experimental bladder cancer implantation model: in vivo and in vitro studies. Wiley Online Library; 2003. pp. 213–219.
  • 12. Benhanifia B, Boukraa L, Hammoudi M, Sulaiman A, Manivannan L. Recent Patents on Topical Application of Honey in Wound and Burn Management. Recent Patents Inflamm Allergy Drug Discov.2011; 5(1):81–86.
  • 13. Majtan J, Kumar P, Majtan T, Walls AF, Klaudiny J. Effect of honey and its major royal jelly protein 1 on cytokine and MMP 9 mRNA transcripts in human keratinocytes. Experimental Dermatol.2010; 19(8):e73–e79.
  • 14. Subrahmanyam M, Sahapure AG, Nagane NS, Bhagwat VR, Ganu JV. Effects of topical application of honey on burn wound healing. Ann Burns Fire Disasters. 2001; 14(3):143–147
  • 15. Shoar S, Esmaeili S, Safari S. Pain Management after surgery: A brief review. Anesth Pain. 2012; 1(3):184–186
  • 16. Al-Waili N, Salom K, Al-Ghamdi AA. Honey for wound healing, ulcers, and burns; data supporting its use in clinical practice. Sci World J. 2011; 11:766–787.
  • 17. Vardi A, Barzilay Z, Linder N, Cohen HA, Paret G, Barzilai A. Local application of honey for treatment of neonatal postoperative wound infection. Informa Healthcare; 1998. pp. 429–432
  • 18. HosseiniJahromi S, Masoumeh S, Hatamian S. Comparison Between Effect of Lidocaine, Morphine and Ketamine Spray on Post-Tonsillectomy Pain in Children. Anesth Pain. 2012; 2(1):17–21.
  • 19. Javid M, Hajijafari M, Hajipour A, Makarem J, Khazaeipour Z. Evaluation of a Low Dose Ketamine in Post Tonsillectomy Pain Relief: A Randomized Trial Comparing Intravenous and Subcutaneous Ketamine in Pediatrics. Anesth Pain. 2012;2(2):85–89.
  • 20. Salonen A, Kokki H, Nuutinen J. The effect of ketoprofen on recovery after tonsillectomy in children: a 3-week follow-up study. Int J Pediatotorhinolaryngol . 2002; 62(2):143-150.
  • 21. Saleh Mohebbi, Fatemeh Hasan Nia, Farbood Kelantari, Sheqhayeqh Ebrahim et al . Efficacy of honey in reduction of post tonsillectomy pain, randomized clinical trial. International Journal of Pediatric Otorhinolaryngology. 2014;78(11):1886-9.