Published June 28, 2022 | Version v1
Dataset Open

MIR142 Sanger sequencing results in MPNs

Authors/Creators

  • 1. 1Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland
  • 2. 2Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland
  • 3. 1Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland;3Institute of Computing Science, Poznan University of Technology, Poznan, Poland
  • 4. Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland

Description

To extend and complement knowledge about the occurrence and/or frequency of MIR142 mutations in hematologic cancers, we sequenced MIR142 in large panels of MPNs [including polycythemia vera (PV), essential thrombocythemia (ET), primary myelofibrosis (PMF), and chronic myeloid leukemia (CML)], blood disorders for which such mutations have never been tested, and in AML and CLL, for which the mutations have been reported. The dataset gathers Sanger sequencing results of the MIR142 locus.

Notes

Dataset from publication Galka-Marciniak et al. 2022, Sci Rep "Mutations in the miR-142 gene are not common in myeloproliferative neoplasms" This work was supported by research grants from the Polish National Science Centre (2016/22/A/NZ2/00184, 2020/39/B/NZ5/01970, and 2020/39/D/NZ2/03106)

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Related works

Is source of
Journal article: 10.1038/s41598-022-15162-1 (DOI)