Published December 1, 2018 | Version v1
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Study of Meconium Aspiration Syndrome in Relation to Birth Weight and Gestational age

Authors/Creators

  • 1. Department of Peadiatrics, MLB Medical College, Jhansi

Description

A prospective observational study conducted in NICU, MLB Medical College, Jhansi. 83 neonates who fulfilled inclusion criteria were studied over a period of 18 months from April 2016 to September 2017. Maternal obstetric history th and risk factors were studied and fetal parameters including gestational age, mode of delivery, birth weight, sex, age at onset of respiratory distress, treatment and outcome were noted. The aim of this study was to know the clinical profile of meconium aspiration syndrome (MAS) in neonates and to access relation of gestation. Survival rate can be increased with a planned team approach during perinatal period. Hence this study was undertaken to understand the clinical profile of neonates with meconium aspiration. Out of these 83, 50 babies (60.24%) were out born. Majority of babies belonged to 2.5- 3.5 kg weight group (n=55, 66.27%) and were male (n=62, 74.70%). 59.04% of babies with MAS were term babies. Most of MAS babies were delivered to primigravida mothers (n=51, 61.45%). MAS were commonly associated with LSCS born babies (n=45, 54.22%). Majority of babies were vigorous (n=50, 60.24%) had downe's score <4 (n=51, 61.45%). MAS occurred most commonly in babies having fetal distress (42.17%) and in mothers with history of PIH (12.05%). Birth asphyxia was one of the most common associated morbidity (38.55%) followed by septicemia (26.54%) among these MAS babies. MAS is an entity which is commonly seen in term and post term babies with birth weight group 2.5-3.5 kg. 

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References

  • 1. Rao B, Chandashekar GS, Rao D, Hegde P, Ghate SV. Meconium stained amniotic fluid. A prospective study: Karnataka. J Paediatr. 2011;25(1):21-26.
  • 2. Shivanna BS, Shivanna L, Rao R. Efficacy of Amnioinfusion for meconium stained liquor in labour in a rural hospital. IOSR. J Dent Medi Scien. 2014;13(5):07-11.
  • 3. Ashtekar SD, Ashtekar RS, Kumbhar SK, Pilgulwar G, Gaikwad NK. Clinical study of meconium aspiration syndrome in relation to birth weight and gestational maturity at general hospital Sangli. Intern Medi J. 2014;1(5):189-192.
  • 4. Narang A, Nair PMC, Bhakoo ON, Vashisht K. Management of meconium stained amniotic fluid: A team approach. J Indian Pediatrics. 1993;30:9–13.
  • 5. Suresh GK, Sarkar S. Delivery room management of infants born through thin meconium stained liquor. Indian Pediatr. 1994;31(10):1177-81
  • 6. Errkola R. Meconium aspiration syndrome. Ann Chir Gynecol Supple. 1994;208:106-109.
  • 7. Sharma U, Garg S, Tiwari K, Hans PS, Kumar B. Perinatal Outcome in Meconium Stained Amniotic Fluid. Journal of Evolution of Medical and Dental Sciences. 2015; 4(48):8319-8327.
  • 8. Tayade S. The Significance of meconium stained amniotic fluid. A cross sectional study in a rural setup. International Journal of Biomedical and Advance Research.2012;3:12.ss
  • 9. Naqvi SB, Manzoor S. Association of meconium stained amniotic fluid with perinatal outcome in pregnant women of 37-42 weeks gestation. Pak J Surg. 2011; 27(4): 292-298.
  • 10. Gauchan E, Basnet S, Malla T. Meconium Aspiration Syndrome and Neonatal Outcome: A Prospective Study. American Journal of Public Health Research.2015;3(5A) 48-52.
  • 11. Nath GDR et al; Study of clinical profile of meconium aspiration syndrome in relation to gestational age and birth weight and their immediate outcome. International Journal of Contemporary Pediatrics. 2017; 4(6): 2142-2150.
  • 12. Hiremath PB, Bahubali G, Meenal C, Bansal N, Ragaramya. The Management Practices and Outcome of Meconium Stained Amniotic Fluid. Int J Biol Med Res. 2012; 3(3): 2204-2207.
  • 13. Chandran JR, Uma DN, Rajeshwary U. Risk Factors For Meconium aspiration And meconium aspiration syndrome in neonates born through meconium stained amniotic fluid in a tertiary care centre in Malabar (Kerala). J Evolu Medi Dent Scien. 2013; 2 (49):9489- 9495.
  • 14. Gupta V, Bhatia BD, Mishra OP. Meconium stained amniotic fluid: antenatal, intrapartum and neonatal attributes. Indian Pediatr. 1996;33:293-8.
  • 15. Behera MK, Kulkarni SD, Gupta RK. Meconium Aspiration syndrome: A Clinical Study Med J Armed Forces India. 1998; 54(1):19-20.
  • 16. Thomas E, Wiswell. The meconium Aspiration Syndrome the saga continues. Indian Paediatr. 1998;35:1059-1062.