Published May 23, 2017
| Version v1
Journal article
Open
On the Integration of In Silico Drug Design Methods for Drug Repurposing
Creators
- 1. Molecular Modelling & Drug Design Lab, Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy
- 2. Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R&D Gothenburg, Mölndal, Sweden
Description
Drug repurposing has become an important branch of drug discovery. Several computational approaches that help to uncover new repurposing opportunities and aid the discovery process have been put forward, or adapted from previous applications. A number of successful examples are now available. Overall, future developments will greatly benefit from integration of different methods, approaches and disciplines. Steps forward in this direction are expected to help to clarify, and therefore to rationally predict, new drug–target, target–disease, and ultimately drug–disease associations.
Files
fphar-08-00298.pdf
Files
(695.8 kB)
| Name | Size | Download all |
|---|---|---|
|
md5:acbc1f7212b13abe276369b4545fc4a9
|
695.8 kB | Preview Download |