Published August 6, 2023 | Version v1
Dataset Open

Olfactory bulb snRNAseq dataset for Team Schlossmacher- ASAP

Authors/Creators

  • 1. Baylor College of Medicine

Description

C57BL/6 mice were nasally inoculated with either a control AAV (AAV-EF1a-TdTomato, B1-4) or an experimental AAV expressing humanized mutant alpha-synuclein (AAV-EF1a-SNCA(A53T), A1-4). The mice were 8 weeks of age at the time of inoculation and the virus was expressed for 4 weeks before the mice were sacrificed and the olfactory bulbs were collected for snRNAseq. Viral transduction of olfactory sensory neurons was confirmed in all 8 samples via cryosectioning of the contralateral olfactory bulb.

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