Phytochemical and Antibacterial Activity of Delbergia saxatilis Leaf Extract

ABSTRACT

Dalbergia saxatilis is widely used in traditional medicine system. The species are used in traditional system of medicine all over the world in the treatment of various ailments qualitative phytochemical analysis and antibacterial activity of the leaf extract were evaluated. Phytochemical analysis was carried out using standard procedure, the bioactive compounds detected were flavonoids, tannins, saponins, steroids, balsam, saponin glycosides, volatile oils, alkaloids, cardiac glycoside and glycosides and absence of anthraqinone,. Antibacterial activity of the leaf extract was also tested against the certain strains of clinical isolates of bacteria such as Streptococcus spp., Escherichia coli and Salmonella typhi using disc diffusion and broth techniques. The antibacterial test result had indicated that the test isolates were sensitive to the leaf extract of Dalbergia saxatilis plant with highest efficiency against Streptococcus spp at 400mg/ml (24mm), 500mg/ml (19mm) for E. coli and then 0.00mm for Salmonella typhi at all concentration. The lowest activity for E. coli and Streptococcus spp was at 300mg/ml (16mm and 19mm) respectively. The leaf extract of the plant found to show strong inhibitory activity against some of the tested organisms at higher concentrations which was in dose dependent manner. The study had indicated that the leaf extract of the plant has potential against microbial infections.