Published July 22, 2023 | Version v1

MECHANISM OF CORNEAL HEALING AND THE ROLE OF THE GROWTH FACTORS IN THE EYE – A REVIEW

  • 1. University of Forestry, Faculty of Veterinary Medicine, Sofia, Bulgaria

Contributors

  • 1. University of Forestry

Description

Injury to the cornea results in a cascade of processes that lead to the healing of the wound and restoration of vision, requiring integration of cellular proliferation, migration, differentiation, apoptosis, and intercellular communication. Combinations of growth factors and cytokines present in the tear film and cornea of the eye are involved in these processes. The presented article reviews the corneal anatomy and the most common lesions of the cornea in veterinary ophthalmology. It overviews the chemical signal-mediated events and the important role of the growth factors as regulators in healing and repairing the corneal cells and the corneal layers.

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