Small NBL Dataset for Analysis of AKT Signaling

ExpressionData.csv

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A small subset of transcriptomics data (30 genes) curated for learning Gene Regulatory Networks (GRNs) pertaining to signaling by the ALK pathway. Genes were selected by referencing the "signaling by ALK" pathway from Reactome (https://reactome.org/content/detail/R-HSA-201556). This subset of data belongs the TARGET-NBL project (https://portal.gdc.cancer.gov/projects/TARGET-NBL), hosted via the Genomic Data Commons Data Portal (https://portal.gdc.cancer.gov/). Please refer to GDCs data access policies (https://gdc.cancer.gov/about-gdc/gdc-policies) if planning to use the data. 

refNetwork.csv

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Contains a reference network of known pairwise regulatory relationships among the genes of which we have transcriptomics data available in "ExpressionData.csv." These relationships were again determined by referencing the "signaling by ALK" pathway from Reactome (https://reactome.org/content/detail/R-HSA-201556).