NURSING DOMAIN
Published July 12, 2023 | Version v1
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Types and Causes of Citrullinemia Type I, Type II, Symptoms of Citrullinemia Type I, Type II, Diagnosis of Citrullinemia, Clinical Evaluation of Citrullinemia and Treatment of Cutrullinemia

Authors/Creators

  • 1. Assistant Professor, College of Veterinary Science, Korutla, PVNRTVU, Telengana, Hyderabad, India
  • 2. Veterinay Doctor, College of veterinary science, Proddatur, Andhra Pradesh, India
  • 3. Associate Professor, College of veterinary science, Proddatur, Andhra Pradesh, India
  • 4. Staff, Indian Veterinary Research Institute (IVRI), Izathnagar, Barielly district, Uttar Pradesh, India
  • 5. Assistant General Manager, Vaishnavi Bio pharma pvt. Ltd., Telanagana, India
  • 6. Assistant Professor, Contract Teaching Faculty, College of veterinary, science, Proddatur, Andhra Pradesh, India

Description

Citrullinemia is a rare genetic disorder that affects the metabolism of the amino acid arginine. It is manifested by the collection of citrulline, a toxic substance, in the blood and tissues due to the deficiency or malfunctioning of an enzyme called argininosuccinate synthetase. This article gives information about the understanding of citrullinemia, along with its causes, symptoms, diagnosis, treatment, and ongoing research efforts.

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References

  • 1. Albayram, S., Murphy, K. J., Gailloud, P., Moghekar, A., & Brunberg, J. A. (2002). CT findings in the infantile form of citrullinemia. American journal of neuroradiology, 23(2), 334-336.
  • 2. Ames, E. G., Powell, C., Engen, R. M., Weaver Jr, D. J., Mansuri, A., Rheault, M. N., ... & Luckritz, K. E. (2022). Multisite retrospective review of outcomes in renal replacement therapy for neonates with inborn errors of metabolism. The Journal of pediatrics, 246, 116-122.
  • 3. Ando, T., Fuchinoue, S., & Shiraga, H. (2003). Living-related liver transplantation for citrullinemia: different features and clinical problems between classical types (CTLN1) and adult-onset type (CTLN2) citrullinemia. Jap J Transpl, 38, 143-7.
  • 4. Bachmann, C. (2003). Outcome and survival of 88 patients with urea cycle disorders: a retrospective evaluation. European journal of pediatrics, 162, 410-416.
  • 5. Batshaw, M. L., MacArthur, R. B., & Tuchman, M. (2001). Alternative pathway therapy for urea cycle disorders: twenty years later. The Journal of pediatrics, 138(1), S46-S55.
  • 6. Bireley, W. R., Van Hove, J. L., Gallagher, R. C., & Fenton, L. Z. (2012). Urea cycle disorders: brain MRI and neurological outcome. Pediatric radiology, 42, 455-462.
  • 7. Bourdeaux, C., Darwish, A., Jamart, J., Tri, T. T., Janssen, M., Lerut, J., ... & Reding, R. (2007). Living-related versus deceased donor pediatric liver transplantation: a multivariate analysis of technical and immunological complications in 235 recipients. American journal of transplantation, 7(2), 440-447.
  • 8. Boy, N., Heringer, J., Brackmann, R., Bodamer, O., Seitz, A., Kölker, S., & Harting, I. (2017). Extrastriatal changes in patients with late-onset glutaric aciduria type I highlight the risk of long-term neurotoxicity. Orphanet journal of rare diseases, 12(1), 1-13.
  • 9. Brunetti-Pierri, N., Lamance, K. M., Lewis, R. A., & Craigen, W. J. (2012). 30-year follow-up of a patient with classic citrullinemia. Molecular Genetics and Metabolism, 106(2), 248-250.
  • 10. Gravel, R. A. (2001). The metabolic and molecular basis of inherited disease. (No Title), 3827.