Published July 5, 2023 | Version v3

Transposable element (TE) subfamily cis-regulatory activities estimated from 441 transgene overexpression experiments in human embryonic stem cells (hESCs)

Authors/Creators

  • 1. Swiss Federal Institute of Technology Lausanne (EPFL)

Description

Additional file 1 from "Statistical learning quantifies transposable element-mediated cis-regulation", Pulver et al.

Raw expression data came from Nakatake et al., Cell Reports 2020

Activities were estimated using craTEs, described in Pulver et al. 2023, with parameter L = 2.5e5 bp.

Rows are transposable element (TE) subfamilies, columns are as follow:

  • Estimate: estimated cis-regulatory activity, correponds to a linear regression coefficient
  • Std. Error: standard error of linear regression coefficient
  • t value: t value corresponding to t-test with H0: Estimate = 0 and HA: Estimate != 0
  • Pr(>|t|) : probability (p-value) of observing a more extreme t value
  • p_adj: p-values adjusted with the Benjamini Hochberg procedure
  • TE: TE subfamily
  • condition: concatenation of the name of the overexpressed transgene and the timepoint
  • transgene: symbol for the overexpressed transgene
  • timepoint: time under transgene induction via DOX treatment

Files

acts_nakatake.csv

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