Published June 24, 2023
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Marking the Micro Details in Potentially Malignant Disorders of Oral Cavity
Authors/Creators
- 1. Bhabha College of Dental Sciences, Bhopal
- 2. All India Institute of Medical Sciences (AIIMS), Bhopal
- 3. RKDF Dental College and Research Center, Bhopal
Description
Background- The malignancy of the oral cavity constitutes the most important group of malignancies
in South and Southeast Asia.The risk increases with the use of tobacco products.
Materials & Methods- Micronuclei frequency scoring was used as a biomarker to identify different
potentially malignant disorders.
Results- Mean micronuclei index was found higher using Hematoxylin and Eosin stain than
Papanicolaou's stainand May Grunwald's stain.
Conclusion- We concluded that the micronuclei frequencies in oral exfoliated epithelial cells using
three different stains- Hematoxylin and Eosin stain, Papanicolaou's stain, May Grunwald's stain may be
useful in predicting the malignant potential of premalignant lesions.
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References
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