Study of Biologically Active Compounds of the Roots of Prangos biebersteinii Karjag.

The roots of Prangos biebersteinii Karjag. collected from Beshbarmak mountains were investigated.
Seven crystalline substances of the coumarin nature were isolated from an acetone extract of P. bieber-
steinii roots using the method of column chromatography (Al₂O3, III-IV degree activity): C16H14049
m.p. 108.0-109.0°C (1), C15H16O3, m.p. 84.0-85.0°C (2), C16H1405, m.p. 145.0-146.0°C (3), C₁6H₁6059
m.p. 109.0-110.0°C (4), C16H₁405, m.p. 141.0-143.0°C (5), C16H1606, m.p. 137.0-138.5°C (6), C₁H6O4,
m.p. 286.0-279.5°C (7). On the basis of physical and chemical properties (elemental composition, melt-
ing temperature) and spectral (UR- and NMR-spectra) data they were identified as isoimperatorin (1),
ostol (2), isooxypeucedanin (3), pranferol (4), peucedanin (5), oxypeucedanin hydrate (6) and bergap-
tol, respective (7).