Published June 13, 2023
| Version v1
Journal article
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The role of diabetes in metastatic melanoma patients treated with nivolumab plus relatlimab
Authors/Creators
- Domenico Mallardo
- Rachel Woodford
- Alexander M. Menzies
- Lisa Zimmer
- Andrew williamson
- Ramelyte Egle
- Dimitriou Florentia
- Alexandre Wicky
- Roslyn Wallace
- Mario Mallardo
- Alessio Cortellini
- Alfredo Budillon
- Victoria Atkinson
- Shahneen Sandhu
- Michielin Olivier
- Dummer Reinhard
- Paul Lorigan
- Dirk Schadendorf
- Georgina V. Long
- Ester Simeone
- Paolo A. Ascierto
Description
LAG3 inhibition for treating metastatic or unresectable melanoma has a reduced efficacy in subjects with T2D, possibly due to a low expression of LAG3. Our data suggest that glycemia should be monitored and maintained within control levels in these patients.
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