INVESTIGATION FOR POSSIBLE ANTIDIABETIC EFFECTS OF TRIDAX PROCUMBENS IN RATS

Tridax procumbens have different medicinal properties due to its active phytochemical constituents and May able to treat diabetes & diabetics complications. Ethanolic extracts of Tridax procumbens was prepared from plant parts are subjected to acute oral toxicity studies and found that the ethanolic extract of Tridax procumbens is safe to use up to the dose of 2000mg/kg. The ethanolic extract of Tridax procumbens was found to be in dose dependent way against alloxan induced diabetes in rats. The reduction of the elevated blood glucose levels in diabetic rats on treatment with the extract at two different concentrations confirmed that ethanolic extract of Tridax procumbens posses Antidiabetic activity & has shown significant effect when compared to Alloxan administration. It needs comprehensive investigations for developing a safe and effective herbal drug. Further research is required to isolate the biomolecules responsible for the antidiabetic and antidiabetic complications.

Keywords: Tridax procumbens, ethanolic extracts, anti diabetic etc.