Custom R scripts and input files for manuscript "Evolutionary histories of breast cancer and related clones"

Supporting files for manuscript "Evolutionary histories of breast cancer and related clones".

Contents:

• Custom R script and an input file (*.txt) to evaluate clonal structure of single-cell derived organoids using the Gaussian mixture models
• Custom R script and an input file (*.txt) to estimate mutation rate in normal organoids using the linear regression models 
• Custom R script and input files (*.txt) to generate mutation matrices for phylogenetic analysis using MEGA and treemut 
• Custom R scripts and an input file (*.txt) to estimate the timing of 1q gain, 1q gain doubling, and MRCA emergence