REVIEW ON MICROSPONGE DRUG DELIVERY SYSTEM

Microsponges are polymeric delivery systems composed of porous microspheres. They are tiny sponge-like spherical particles with a large porous surface. Moreover, they may enhance stability, reduce side effects and modify drug release favorably. Microsponge delivery technology has many favorable characteristics, which make it a versatile drug delivery vehicle. Microsponge systems are based on microscopic, polymer based microspheres that can suspended or entrap a wide variety of substances, and can then be incorporated into a formulated product such as gel, cream, liquid or powder. The outer surface is typically porous, allowing a sustained flow of substance out of the sphere. Microsponges are porous, polymeric microspheres that are used mostly for topical use and have recently been used for oral administration. Microsponges are designed to deliver a pharmaceutical active ingredient efficiently at the minimum dose and also to enhance stability, reduce side effect, and modify drug release.