FORMULATION AND EVALUATION OF HERBAL TABLETS FOR DIABETES AND HYPERTENSION

Increased circulatory fluid volume and peripheral vascular resistance are closely associated to elevated blood pressure. Patients with diabetes mellitus experience increased peripheral arterial resistance brought on by vascular remodeling, as well as an increase in body fluid content brought on by hyperinsulinemia and hyperglycemia brought on by insulin resistance. These two processes both raise blood pressure throughout the body. Since type 2 diabetes has a natural history, understanding the pathophysiology of hypertension in diabetes mellitus needs familiarity with this condition. Due to poor glucose tolerance and early-stage diabetes, patients have hyperinsulinemia and insulin resistance. Increased bodily fluid content is the cause of hypertension. Diabetes has advanced to the mid-stages at this point, and peripheral vascular resistance and vascular remodeling both play a role in hypertension. Additionally, vascular remodeling has a big impact on diabetes complications. Particularly, higher glomerular pressure is brought on by afferent arteriolar remodeling during diabetic nephropathy. Our present work deals with the development and evaluation of herbal tablet which is used for the treatment of diabetes and hypertension containing paneer phool shatavari, Arjunsal, S.musli ,Chirayata , Kutaki, Shilajit Stevia etc . All the above mention plant ingredients were reported for having good antidiabetic antihypertensive and antioxidant activity.

KEY WORDS:  Paneer phool shatavari, Arjunsal, S.musli ,Chirayata , Kutaki, Shilajit Stevia, Vijaysar.