The effect of dietary bioactive on gut microbiome diversity (DIME) – a pilot study

The DIME study consists of a randomised 2x2 cross-over human intervention where healthy participants (n = 20) are subjected to a diet high in bioactive-rich food for two weeks and a diet low in bioactive-rich food. There is a four-week washout between the two interventions. 

The continuous glucose monitoring was achieved using the Abbott freesylte libre flash glucose device. The baseline of the participants were determined 7 days before the start of the intervention, followed by the first arm and second arm. The period between the two arms (washout) was not recorded.

We also included sleep data which consists of the amount of time spent in bed and during that time the amount of time spent in light, deep and rem in all 20 participants during the course of the dietary intervention, both the high and low bioactive diet.  that was captured using Fitbit wearables during both stages of the dietary intervention,