Published May 30, 2023
| Version v1
Dataset
Open
Imaging data from "Live-cell 3D single-molecule tracking reveals modulation of enhancer dynamics by NuRD"
Authors/Creators
-
Basu, Srinjan1
- Shukron, Ofir2
- Hall, Dominic3
- Parutto, Pierre4
- Ponjavic, Aleks5
- Shah, Devina3
- Boucher, Wayne3
- Lando, David3
- Zhang, Wei3
- Reynolds, Nicola6
- Sober, Louisa H.3
- Jartseva, Aleksandra3
- Ragheb, Ramy6
- Ma, Xiaoyan3
- Cramard, Julie6
- Floyd, Robin6
- Balmer, Jenny3
- Drury, Tom3
- Carr, A. R5
- Needham, Lisa-Maria5
- Aubert, Alice7
- Communie, G.7
- Gor, Kavan6
- Steindel, Maike6
- Morey, Lluis8
- Blanco, E.8
- Bartke, Till9
- Di Croce, Luciano8
- Berger, Imre10
- Schaffitzel, Christiane10
- Lee, Steven F.5
- Stevens, Tim J.11
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Klenerman, David5
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Hendrich, Brian D.6
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Holcman, David4
-
Laue, Ernest D.3
- 1. Wellcome-MRC Cambridge Stem Cell Institute
- 2. Department of Applied Mathematics and Computational Biology, Ecole Normale Supérieure, France
- 3. Department of Biochemistry, University of Cambridge
- 4. Department of Applied Mathematics and Computational Biology, Ecole Normale Supérieure
- 5. Yusuf Hamied Department of Chemistry, University of Cambridge
- 6. Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre
- 7. The European Molecular Biology Laboratory EMBL
- 8. Centre for Genomic Regulation (CRG)
- 9. Helmholtz Zentrum München
- 10. School of Biochemistry, University of Bristol
- 11. MRC Laboratory of Molecular Biology Cambridge
Description
3D 20ms, 3D 500ms and 2D dCas9 raw videos, localisation, tracking and trajectory analysis data
From 'Live-cell 3D single-molecule tracking reveals modulation of enhancer dynamics by NuRD" (2021). Biorxiv. https://doi.org/10.1101/2020.04.03.003178
Files
20ms_CHD4.zip
Files
(140.2 GB)
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md5:5af158e2724736d37e0d369f8d4f56c9
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md5:56b90a07afb2e66a7f89f1e2b761cae2
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md5:a9b1c08124759fab06db2c7fa7e8ae36
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14.4 GB | Preview Download |
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md5:11978f73076ec13616ae8eb3c965f39e
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9.1 GB | Preview Download |
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md5:ac5304a6bc3b318a19f5b9de56918dc8
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38.6 GB | Preview Download |
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md5:a076371e8f61f8ea3962fdb506808df1
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14.7 GB | Preview Download |
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md5:c3d575a4cdf8d71576f665d22d076636
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242.2 MB | Preview Download |
Additional details
Related works
- Is published in
- Preprint: 10.1101/2020.04.03.003178 (DOI)
Funding
- UK Research and Innovation
- Understanding how the NuRD complex regulates ES cell differentiation using single molecule fluorescence imaging MR/M010082/1
- Wellcome Trust
- Understanding mammalian interphase genome structure in mouse ES cells 206291
- European Commission
- 4DCELLFATE - Developing a global understanding of the PRC and NuRD complexes in stem cell differentiation, in health and disease 277899
- UK Research and Innovation
- Transcriptional control of cell fate decisions by chromatin remodelling proteins MR/R009759/1
- UK Research and Innovation
- Understanding how the NuRD complex assembles and functions in mouse embryonic stem cells (mESC's) MR/P019471/1
References
- Basu, Shukron et al. (2021) Biorxiv. https://doi.org/10.1101/2020.04.03.003178