Published June 3, 2023
| Version v1
Dataset
Open
Characterization of mAMCase sugar-binding subsites
Description
This directory contains all files required to characterize sugar-binding subsites across mouse AMCase structure 8FR9, 8FRA, and 8GCA as presented in Figure 2 of Díaz et al. (2023).
Structure models were analyzed in PyMOL. Figures were compiled using Adobe Illustrator.
Files included in this directory:
Figures
- contains PNGs of all sugar-binding subsites, canonical subsites, and noncanonical subsites with and without 2fo-fc electron density displayed.
PyMOL
- contains all structural models, 2mFo-DFc maps, mFo-DFc maps, PyMOL script, and PyMOL session used to generate Figure 2.
Contact:
Roberto Efraín Díaz, robertoefrain.diaz@ucsf.edu
James Fraser, jfraser@fraserlab.com
Files
Sugar-binding subsites.zip
Files
(358.2 MB)
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Additional details
Funding
- Targeting chitin in fibrotic lung disease 5R01HL148033-03
- National Institutes of Health
References
- Díaz, Roberto Efraín et al. (2023). Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase.