TOXICITY STUDIES - AN OVERVIEW

Toxicity testing is critical in the evaluation of novel medications before they are used on humans. The goal of toxicity testing is to identify any potential hazardous consequences that a test chemical may have, not merely to determine how safe it is. The main goals of toxicity testing are to determine how test compounds affect lab animals and whether they have any direct hazardous effects on humans. Secondly, high doses of test substances are given to lab animals in order to assess any potential risks to humans who receive much lower levels. The current review aims to highlight the importance of toxicity testing. Toxicity testing is of the following types: Acute toxicity studies, sub-acute toxicity studies, and chronic toxicity studies are the three different categories of toxicity testing. A variety of tests were used in animal species for toxicity testing, including long-term drug administration, regular monitoring of physiological and biochemical abnormalities, and a thorough post-mortem examination at the conclusion of the trial to look for obvious or histological abnormalities. Because animals are useful for studying a functioning organism as a whole, their employment in toxicity testing is most likely to continue for the foreseeable future.