Published October 23, 2019 | Version v1
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The Establishment of Human Hookworm, Necator americanus in Hamsters - A Retrospective Look

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  • 1. Chief Scientific Consultant, BioMedical Research and R&D of Health Care, Biofirm Pty Ltd, Australia

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Abstract

The developmental cycle of adaptation of human hookworm, Necator americanus into laboratory rodent host hamster, is being critically reviewed. This laboratory model is found to be reliable one and recommended for various biological experimentations. This model is undoubtedly representing all aspects of human hookworm biology, and for elucidating activity of chemotherapy and planning control experimentation. Adapted - hookworms are now available and can be sourced either from University of Nottingham, England or from Prof SH Xiao Shanghai, China. Further this model may prove useful for assessment of newer anthelminthics and to study the protective immune responses against the infection provided careful planning and windows of assessment be carried out under controlled conditions.

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Biomedical Research and Reviews (ISSN:2631-3944)

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