Published May 8, 2023 | Version pdf
Journal article Open

Dynamics Of Neuroendocrine System In Postnatal Development Of Stress Affected Fetus In Prenatal Period

  • 1. Research Center of Azerbaijan Medical University
  • 2. Research Obstetrics and Gynecology Institute, Ministry of Health of the Republic of Azerbaijan
  • 3. Obstetrics and Gynecology Department, Azerbaijan Medical University

Description

Dynamics of changes in biogenic amines and hormones in baby rats whose mothers affected by emotional
stress reactions during pregnancy has been presented in this article. For this purpose, the research on rat
babies carried out for 5 months, concentrations of dopamine (DA), noradrenaline (NA), serotonin, 5-OT and
5-oxyindolacetic acid (5-OIAA) in blood and hypothalamus, and activity of hormones in blood were studied
during these months. The results showed that DA and NA amounts in blood and hypothalamus of rat babies
whose mothers were affected by stress reactions during pregnancy were higher compared with normal babies
during the entire research. However, activity of 5-OT and 5-OIAA decreased in both environments.
Accordingly, hormonal indicators changed sharply. Adaptive and reproductive functions were violated and
developmental rate was relatively weak in these babies.

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