Published May 2, 2023
| Version v1
Preprint
Open
Parkinson's VPS35[D620N] retromer lysosomal dysfunction induces LRRK2 mediated lysosomal association of RILPL1 and TMEM55B
Description
Primary data associated with the manuscript "Parkinson’s VPS35[D620N] retromer lysosomal dysfunction induces LRRK2 mediated lysosomal association of RILPL1 and TMEM55B" (Prosenjit Pal, Matthew Taylor, Pui Yiu Lam, Francesca Tonelli, Chloe A. Hecht, Pawel Lis, Raja S. Nirujogi, Toan K. Phung, Emily A. Dickie, Mel Wightman, Thomas Macartney, Suzanne R. Pfeffer and Dario R. Alessi). These include raw immunoblotting data (annotated .tiff exports of Image Studio Lite Licor scans) with their quantitation (.xlsx files) and graphs with statistical analysis obtained using GraphPad Prism (.pzf files).
Files
Files
(174.9 MB)
| Name | Size | Download all |
|---|---|---|
|
md5:00f687de3bbe452699e15b24a85a769c
|
36.5 kB | Download |
|
md5:624492d8ff4f32255b5e7b300831bc6b
|
23.1 kB | Download |
|
md5:0a748d0a3b01f7bfdebb9f988e4e8c68
|
182.0 kB | Download |
|
md5:bd49732e50cdae29661e79e4f61973dd
|
16.0 kB | Download |
|
md5:0fc4fe0e51b65d517c51d58af14eb162
|
17.3 kB | Download |
|
md5:c9f8bd6dddf05c427af5edc29860192b
|
17.9 kB | Download |
|
md5:0bec6b37e8a2d0e9f421555c90fc8188
|
19.7 kB | Download |
|
md5:f83497add9cf188c01590f039cad5b85
|
16.3 kB | Download |
|
md5:644b1c635f24979ea0366434da1e4475
|
31.5 kB | Download |
|
md5:21e0ebde2ffe5a9ea6949d13efedff8e
|
19.7 kB | Download |
|
md5:07d283b6d94eac1e67898c593355d04f
|
17.8 kB | Download |
|
md5:7941777966c8be8dc02a0040194b9e89
|
13.6 MB | Download |
|
md5:9e37a25d917a0711d63bfb0dfc28a751
|
13.6 MB | Download |
|
md5:8544046a2929b70baaae8d85997f9c74
|
21.5 MB | Download |
|
md5:a729b3cd42f3171964070d25bb1f3a84
|
21.5 MB | Download |
|
md5:b16f1b4805983134bdf327070a8de7f2
|
24.1 MB | Download |
|
md5:ce556fc69883f12ce456a1c0016242d8
|
24.1 MB | Download |
|
md5:5a1441958cf8e55ff5396c6e58a568cc
|
22.3 MB | Download |
|
md5:bc697497ced7b74f802fa77c64ad99a0
|
22.3 MB | Download |
|
md5:8e47cee4a610fbdc96c7c7b6d766ece8
|
93.5 kB | Download |
|
md5:7507ffcc62fd75d7b1eee8b4b40b7eae
|
30.0 kB | Download |
|
md5:b9f4c0a44e2c08871449009ddcbab0fa
|
93.9 kB | Download |
|
md5:5e383fc090588384cb757536c469130c
|
64.3 kB | Download |
|
md5:2992ff4ccaf6207c93694bb86c41d532
|
11.0 kB | Download |
|
md5:010e92e65bb33ad14e6c05e347bfd4fe
|
96.8 kB | Download |
|
md5:c1cb3f9050c337753513019500e09d4a
|
54.2 kB | Download |
|
md5:ec473a0a2d004064c028c65847249500
|
49.1 kB | Download |
|
md5:0257ad9acc48f116e7fdfea887e475f0
|
49.3 kB | Download |
|
md5:308b8a49b8cfccd00e3bd438cf1c973a
|
47.3 kB | Download |
|
md5:76da52cb63dc967341c5530edf51e897
|
66.1 kB | Download |
|
md5:94f4d03f24e6e079e3c9e69022582ed3
|
680.1 kB | Download |
|
md5:f1b15efd2dbc3176affa64f4c415f1a5
|
104.3 kB | Download |
|
md5:bc3d62ecb04197a74c4e7cd4de31a7c4
|
138.6 kB | Download |
|
md5:932cad2d56e76ab500a442e110cba604
|
113.6 kB | Download |
|
md5:25b1976e1f4707802d3c10a01cc25e9e
|
39.4 kB | Download |
|
md5:f8352e8978ddbf71a60be4f4fc5a91fe
|
26.6 kB | Download |
|
md5:fa54db9968771ab38852934753ac2c35
|
39.9 kB | Download |
|
md5:3fc7ac77db6933dda24ca439b59be46b
|
57.4 kB | Download |
|
md5:db155beb057762858226f9bd24500965
|
34.9 kB | Download |
|
md5:c3ae7d726eb3d403bc630744c9668465
|
26.6 kB | Download |
|
md5:ce493726e2d236a718af4a70a19aa3f1
|
30.5 kB | Download |
|
md5:1d37c5d4e8a34b819ebf49ead0487838
|
29.0 kB | Download |
|
md5:f470a5cdde05b26294ed289456adb12f
|
18.5 kB | Download |
|
md5:ae7e57b43a8e4a558b23227dbdfa1a4e
|
129.4 kB | Download |
|
md5:61d0dc5a84fff2614e7a4bf3c71f806e
|
75.9 kB | Download |
|
md5:71c7c99dd6e445cfaa38604824f8f958
|
117.8 kB | Download |
|
md5:a9a1e05fa2ce502f464a4fd797c393d9
|
64.0 kB | Download |
|
md5:c7c8096394db7ee89310f5af5a410a00
|
44.8 kB | Download |
|
md5:49152275e75a01adb9c0e6c6c38c4ee2
|
39.8 kB | Download |
|
md5:24cecf2bbb1393bbf71c1e6b4548cd6e
|
22.9 kB | Download |
|
md5:4f4f1bc41c635b3afbf687f4b68d929d
|
199.2 kB | Download |
|
md5:77ef9ae5ca3d6cdc41970701ee45bfe2
|
89.7 kB | Download |
|
md5:6be86174e05d8a2d87cac41b1bd3d132
|
53.9 kB | Download |
|
md5:759e50fabef4a61aa3b2b2903f22f54a
|
71.4 kB | Download |
|
md5:ab3de646b2a0c42c051d8c4442cd1d59
|
69.5 kB | Download |
|
md5:31879146ddb305dee22326114e3792ec
|
47.5 kB | Download |
|
md5:55af50e128b06277ce5b99792d29e00a
|
53.2 kB | Download |
|
md5:1b599c7d065d0af6fe793454aa366bab
|
43.6 kB | Download |
|
md5:6a549422c07a1423d6a7a1d9173c521a
|
49.3 kB | Download |
|
md5:5d31f56bd2d200a6c1440b6c2143f296
|
64.6 kB | Download |
|
md5:7fe299348fe38c5b0d31c4fea6c01e23
|
70.1 kB | Download |
|
md5:e699913a39089dcaca71c8471c854aad
|
53.4 kB | Download |
|
md5:2e2dee9d0d06c24f8de460855378978a
|
55.3 kB | Download |
|
md5:7b2ed49b857e8ca910ffd3aef3177683
|
54.9 kB | Download |
|
md5:338f84d2b1f07ca2f464b24cf7662e21
|
96.9 kB | Download |
|
md5:16c3670f8b997993b411a3fb44fcea6e
|
58.6 kB | Download |
|
md5:84adb78e6d0c6c20b13bb9e454cff111
|
72.4 kB | Download |
|
md5:7dfd37ede5b34bd63c9f888e3f00f755
|
63.3 kB | Download |
|
md5:2a3586bd75e31cf4415e5176ad8ea503
|
65.7 kB | Download |
|
md5:2cb2efbfe6ff9f22a8142dc526d88ca7
|
66.7 kB | Download |
|
md5:34cd6f249b22069aebb4ca21ec6d9948
|
47.0 kB | Download |
|
md5:6649f0a527d137887140fed1dbf8faf4
|
54.7 kB | Download |
|
md5:0e7b3b6ad3c26a449c659af26fbfc6eb
|
55.5 kB | Download |
|
md5:520b05defa7c23282fd83af8ea542d0b
|
55.5 kB | Download |
|
md5:7ae65d67bcfcecdf4e3c2edd8ce0276e
|
72.9 kB | Download |
|
md5:78230ce5e81f7cdec13ca08f13382bcc
|
64.6 kB | Download |
|
md5:9c48023331edd34faeb78edad1d3e608
|
46.5 kB | Download |
|
md5:94ad983e08d1f10aad1959fe97542109
|
707.0 kB | Download |
|
md5:a0fdc7e2bf3b7110fe228ea4ffce52af
|
44.7 kB | Download |
|
md5:028ffd9fbbafc34ebdc723608627999d
|
20.9 kB | Download |
|
md5:8094c6ab38b327925e0e3ac3b6bac19b
|
316.7 kB | Download |
|
md5:8cc1bfde308bc1a6dac637a3236fb28a
|
5.0 kB | Download |
|
md5:077a87027ad9f81bd72933c9b6b40e0c
|
6.9 kB | Download |
|
md5:577ffa2bfdc8935951a0b1f4ab578f01
|
4.8 kB | Download |
|
md5:fccf4de962b6c20f4f4b7486a582fff4
|
4.2 kB | Download |
|
md5:304a95a675fd806334dcccbaa17d1ae4
|
7.1 kB | Download |
|
md5:92833aaa57bfe1a99b54812c5b888cc7
|
3.8 kB | Download |
|
md5:45bcffbcc135bec48562e53ef81d481c
|
4.2 kB | Download |
|
md5:6dc447382747975e60532f38d229cc74
|
5.8 kB | Download |
|
md5:23b5d18cc3581ac68724029935846ef2
|
6.5 kB | Download |
|
md5:a82a5095eb24342ae70bdb2420d36b72
|
13.4 kB | Download |
|
md5:87764af518aea378dccaf6d2e177f96f
|
8.1 kB | Download |
|
md5:c35337eb66dd84c98a85ec55d26e7944
|
4.0 kB | Download |
|
md5:23f1e7596d846749defe303cd21d7db3
|
6.6 kB | Download |
|
md5:efb1d89e73460d07aa51e5a7914edaba
|
2.5 kB | Download |
|
md5:d5ad95ff9407f060446049511d6188ca
|
3.9 kB | Download |
|
md5:82be951e6bcd0576fdb22caab6900768
|
5.5 kB | Download |
|
md5:aa44c49d2e6d7c0a52655eae7ad249b9
|
5.3 kB | Download |
|
md5:1d1a67ee2bc0147026f30acb28cf5324
|
10.0 kB | Download |
|
md5:5fbbc62510933ffe9e2fa1d7a6a1e507
|
5.4 kB | Download |
|
md5:05d251ecf574b531e34bd22a5a7dda4c
|
6.7 kB | Download |
|
md5:9fc4e236286523a8cfe035145870302b
|
3.4 kB | Download |
|
md5:d6af8ab9a888a37ea54adec0337a83ea
|
14.6 kB | Download |
|
md5:f154bfb6591555866ed304402e07ee36
|
6.4 kB | Download |
|
md5:e467bfe96522ab77d70906fb84537783
|
3.4 kB | Download |
|
md5:2c919eb10f2596b56b1748b98aa8234e
|
3.8 kB | Download |
|
md5:8657c0c7496a0eba3fa01c8ab83d2dc9
|
2.8 kB | Download |
|
md5:36e83c1c2073c52f22db938151a4b128
|
4.7 kB | Download |
|
md5:4251f26ebf5c4a942bcb945ca9950b02
|
6.9 kB | Download |
|
md5:76f6ded88f8487674a1d550962af039a
|
6.7 kB | Download |
|
md5:d7e7911e05a31853469daaf149745d1a
|
5.0 kB | Download |
|
md5:35b295942c7ba15439f52b20cc0001d4
|
3.1 kB | Download |
|
md5:e3374a396983e8db52e83e2a542e2df7
|
4.8 kB | Download |
|
md5:47b2e23bb0ae3f66ffe15ac62cf18037
|
6.0 kB | Download |
|
md5:c8bdc5528216b4de1c535f35c4b0f6a3
|
7.6 kB | Download |
|
md5:896dabcc9aa487a01f7436bb34ba5edd
|
4.3 kB | Download |
|
md5:fbe57b061aa9365a690e900e1f7ba01c
|
10.4 kB | Download |
|
md5:a988192fbc99d49daeb8d9660d69440d
|
6.6 kB | Download |
|
md5:813f75861e5c7e5fef797ca5fa7b44cb
|
12.5 kB | Download |
|
md5:f60099aed875ecb4e10bb08b004e4ddf
|
5.0 kB | Download |
|
md5:754e3dd903b2828add4554d31b7bd661
|
44.3 kB | Download |
|
md5:1b3c6f0259dc3fd93a56f286810594d7
|
11.4 kB | Download |
|
md5:b6f8893c4c7c658bfc7db4d6d6ffcc4c
|
13.0 kB | Download |
|
md5:bc1495434d1ab71893d0b55ba4a8d469
|
8.0 kB | Download |
|
md5:c38eaf2ffa5246baed6adf3abbc1e7d4
|
7.9 kB | Download |
|
md5:0ee3945910214e5d656f001c823e8018
|
4.0 kB | Download |
|
md5:f609b520f0dd0d92c002604db78eb87c
|
6.9 kB | Download |
|
md5:a114f66c24ad0caf172131d6fe44ed02
|
43.9 kB | Download |
|
md5:34934325e4e376e93a038a82279a418b
|
6.4 kB | Download |
|
md5:67c300ca4e354b1b45d41b67129062e3
|
17.0 kB | Download |
|
md5:42ac157a1d2bbd15fc66cb882a1ddb88
|
5.8 kB | Download |
|
md5:ba0b341c5cea4209abcd807d1ccf5135
|
5.5 kB | Download |
|
md5:91bb30d9968ae5d16cbe05616ebd8ab3
|
7.5 kB | Download |
|
md5:a0f6ba635272f4b865f4d923f9e3b9c5
|
12.1 kB | Download |
|
md5:9b1c0dc93d7753b0c483b8b805eb8b91
|
10.2 kB | Download |
|
md5:cfcab623de598989564dbc936acd61e3
|
17.7 kB | Download |
|
md5:517e56fa347da00a01925ba23e594121
|
3.8 kB | Download |
|
md5:9966b5e2304af412bd1b4ce10d036233
|
21.3 kB | Download |
|
md5:7cbabf17ce745d7c969db09f0847a366
|
14.3 kB | Download |
|
md5:9c2062ccf9f706b2feb6338781c8ee07
|
3.4 kB | Download |
|
md5:9f0a051e8973c546cbec791aa755d907
|
4.7 kB | Download |
|
md5:328bee737048fa503b738407eef342bf
|
16.6 kB | Download |
|
md5:8e169abc06297c4d5b9cd7cc118d4218
|
17.9 kB | Download |
|
md5:ce9f1242036d937e94ccf690b51ff88e
|
6.8 kB | Download |
|
md5:60f635afd0a0bb29c634ee8403db90bb
|
9.3 kB | Download |
|
md5:896ffa2666e2bc9fab6c407c5a2f408a
|
17.1 kB | Download |
|
md5:7d35dc90b79b739c6801e1c31d47767b
|
74.0 kB | Download |
|
md5:573250da752df1acf2360426baf9322c
|
15.1 kB | Download |
|
md5:488abbff774794812e7b436563d8fdcd
|
13.1 kB | Download |
|
md5:75b4bd683d4598893f6b98e485737796
|
10.0 kB | Download |
|
md5:771a6333e0b97e115257219a36396395
|
28.7 kB | Download |
|
md5:f64282724fd2cf391a1b428c26cace8c
|
17.9 kB | Download |
|
md5:685e3a082a0bca5cec8d85511519831e
|
10.0 kB | Download |
|
md5:abf7ce39bfd0e82d4de55361fee531b6
|
11.5 kB | Download |
|
md5:e2ebe49d0410db6c425798b35b490ae7
|
13.4 kB | Download |
|
md5:a265c044e20709335005212b037bf979
|
26.2 kB | Download |
|
md5:e7c973fd868524c23b6174f490ad5e98
|
13.5 kB | Download |
|
md5:aa8578e6cc35055ba589f424080c6a10
|
17.7 kB | Download |
|
md5:05f8c2e0c632f39801ff4938d97a0076
|
9.7 kB | Download |
|
md5:7f308fba0903e2c3f80321f8e9c01c53
|
10.4 kB | Download |
|
md5:06dc1d838c9298a2ffc5308925141d94
|
4.8 kB | Download |
|
md5:e61d31ac2ede45f853d61b389ce6e9e1
|
6.0 kB | Download |
|
md5:b09eefeba02956d8dbdf712b00953b52
|
16.0 kB | Download |
|
md5:b71948cc93005821b49c1460295f20c9
|
25.4 kB | Download |
|
md5:5dcdad05c09edaab231171fc5c9e3e92
|
21.0 kB | Download |
|
md5:15259dce8f634db8e79f9e45b7be08bc
|
5.5 kB | Download |
|
md5:440511d66032ac50e796c79dfd8aa18d
|
6.0 kB | Download |
|
md5:b1ac8b0c491baa25d709ae7e6090e1f2
|
56.6 kB | Download |
|
md5:f7bc1467771b59903709aab27bf67418
|
42.7 kB | Download |
|
md5:1827111b362a85c1ecadf5532dfc9313
|
12.7 kB | Download |
|
md5:79400faaf66acaf095bb9da6868e9542
|
56.1 kB | Download |
|
md5:9b11ce43649fe891490a8c5ae69c496e
|
60.7 kB | Download |
|
md5:1c7f2270d310e4ec93a5f3cfbfb6337e
|
47.4 kB | Download |
|
md5:7986f9e212c07382bb3e66d37b8e6eb0
|
500.6 kB | Download |
|
md5:89dc03fecea3352b7509f4a4cecc61f9
|
84.5 kB | Download |
|
md5:6276b00c6eccf3d372d5fd6faed37d1f
|
229.6 kB | Download |
|
md5:f287b175f03ceada20f45265a55af88c
|
522.3 kB | Download |
|
md5:73fddd0033959abcbd167cdea8bd430b
|
51.2 kB | Download |
|
md5:7dbe3ff0b61edc4b7a7a2cd50693ea6a
|
377.0 kB | Download |
|
md5:9f72f406d68cbe955be81ff61ee5291f
|
490.5 kB | Download |
|
md5:8befe6ba72a5a6aada505e2b9f917690
|
57.9 kB | Download |
|
md5:a1573be317f05c7f50d1a5626304c85d
|
13.1 kB | Download |
|
md5:ff48520d691fd06e434cafb861f74d74
|
15.6 kB | Download |
|
md5:3a6d9434cba44620d04c43bfa45c2733
|
55.1 kB | Download |
|
md5:06153590a22b242cccf4919c1cb3ee1d
|
95.7 kB | Download |
|
md5:58ce5ad74c0abac1f690c179a4896524
|
280.3 kB | Download |
|
md5:4e009dd4b172d0581256bd1051f93186
|
97.0 kB | Download |
|
md5:ca5a037735dd8eee6173c5576db2f0c2
|
39.3 kB | Download |
|
md5:e4e5c9fba3633805372a9062d65bed7b
|
71.8 kB | Download |
|
md5:ab0c27b59e637e805d1bcb59a34f1782
|
226.8 kB | Download |
|
md5:f3911babc06447e899e8ed5f338ee92b
|
52.6 kB | Download |
|
md5:00d21a4d45d0fcefc9f732d87f2ad043
|
108.7 kB | Download |
|
md5:1ee53f496597ab2530b1d6fafde1f406
|
98.8 kB | Download |
|
md5:122c9414256b0e43c1f71045663807af
|
1.5 MB | Download |
|
md5:3eb3d10d45cbdd83cbc085f477822520
|
30.4 kB | Download |
|
md5:459d4469a1f6da9958d0b7a47465a0fd
|
37.1 kB | Download |
|
md5:17e79a42addd3282955dc3068060efda
|
13.1 kB | Download |
Additional details
Funding
- Aligning Science Across Parkinson's
- Mapping the LRRK2 signalling pathway and its interplay with other Parkinson’s disease components ASAP-000463