Published April 22, 2023 | Version v1
Journal article Open

The cost of bad science: A PhD student testimonial

Authors/Creators

  • 1. The Sainsbury Laboratory

Description

Read it on medium (recommended).

Rawit, a Thai student, was awarded a scholarship to spend a year studying at Oxford University. Things didn’t go to plan.

Rawit Longsaward is a Ph.D. student at Mahidol University in Thailand. In 2021/2022, he was awarded a scholarship to spend a year in the Plant Chemetics Laboratory of Renier van der Hoorn at the University of Oxford. His objective was to study the extensively researched ribonuclease activity of plant defense-induced proteins belonging to the PR-10 family. Although his account of the events is detailed below, it is disheartening to note that his experience is not unique. 

The prevalence of bad science can be expensive and carries a significant cost for those attempting to build upon it, both in terms of financial resources and wasted effort. Scientific research that is flawed, incomplete, or based on inaccurate assumptions can lead to incorrect conclusions and misguided recommendations. In addition to wasting time and resources, bad science can also have serious consequences for public health, safety, and the environment.

And try to get journals to publish contradictory data, meaning the incentives for early career scientists to work on fixing the scientific record are limited. At least, these days we have the preprint server bioRxiv to highlight “Contradictory Results”.

Enough said. Let’s hear it in Rawit’s own words.

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Additional details

Funding

UK Research and Innovation
Mechanisms of pathogen suppression of NLR-mediated immunity BB/V002937/1
UK Research and Innovation
Genome evolution of a pandemic clonal lineage of the wheat blast fungus BB/W008157/1
UK Research and Innovation
Recognition BBS/E/J/000PR9795
UK Research and Innovation
Engineering CC-HMA-NLR immune receptors for disease resistance in crops (ERiC) BB/W002221/1
UK Research and Innovation
Susceptibility BBS/E/J/000PR9797
UK Research and Innovation
Response BBS/E/J/000PR9796
European Commission
BLASTOFF - Retooling plant immunity for resistance to blast fungi 743165
UK Research and Innovation
Evolution BBS/E/J/000PR9798