LABORATORY DIAGNOSIS OF DRUG ALLERGY. IN VITRO AND IN VIVO TESTS ARE USED FOR DRUG ALLERGY DIAGNOSIS.

Cross-allergic reactions to drugs is a phenomenon of the development of a repeated reaction when prescribing drugs that have similar antigenic determinants (epitopes). Non-protein medical chemicals often have specific structural moieties (critical determinants) that induce the development of allergic hypersensitivity to drugs. The possibility of developing such reactions should always be considered when prescribing any therapy to patients with a history of LA. It should also be borne in mind that there are combination drugs, vaccines containing drugs for which there was a history of an allergic reaction, and drugs that are chemically related to the pharmacological group of causally significant.