A complete list of filtered variants and gene lists of frequently and recurrently mutated genes in 25 MCL patients at diagnosis compared to relapse, as well as a CNV genelist
- 1. Institute of Pathological Physiology, First Faculty of Medicine, Charles University, Prague, Czech Republic; First Department of Medicine- Hematology, University General Hospital Prague and First Faculty of Medicine, Charles University, Prague, Czech Republic
- 2. Institute of Pathological Physiology, First Faculty of Medicine, Charles University, Prague, Czech Republic
- 3. Childhood Leukaemia Investigation Prague, Department of Pediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague
- 4. First Department of Medicine- Hematology, University General Hospital Prague and First Faculty of Medicine, Charles University, Prague, Czech Republic
- 5. Institute of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic
- 6. Center for Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, Charles University and General University Hospital, Prague, Czech Republic
Description
Supplemental Table 1 shows a complete list of variants which passed filtering described in supplemental methods, that were found in both diagnostic samples and relapsed samples (i.e., shared variants, sheet 1A), variants that were newly detected – N/D (sheet 1B) or newly undetected – N/U (sheet 1C). Gene lists for filtration of variants and CNV changes in genes of special interest are included in the table (sheet 1D). Chr - Chromosome, REF - Reference allele, ALT - Alternative allele, AA change - Amino acid change, DG_AF – Variant Allele frequency in the diagnostic sample, DG_Depth - Read depth in the diagnostic sample, REL_AF - Variant Allele frequency in the relapsed sample, REL_Depth - Read depth in the relapsed sample, SNV - Single Nucleotide Variant, and CNV - Copy Number Variation.
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