Published May 25, 2023 | Version v1

To fold or not to fold: diastereomeric optimization of an α-helical antimicrobial peptide

Description

The upload contains additional primary data associated with the publication https://doi.org/10.1021/acs.jmedchem.3c00460, including raw data in the original file format whenever possible.

Data content: HPLC-MS for characterization and serum stability, HRMS, CD, Vesicle leakage, Cytotoxicity, Molecular Dynamics, Crystallography (primary electron density maps), pictures for microbiological and hemolysis assays and Supporting Information.

Files

1.Liquid_chromatography.zip

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Additional details

Related works

Is published in
Journal article: 10.1021/acs.jmedchem.3c00460 (DOI)

Funding

Swiss National Science Foundation
Chemical Space Design of Small Molecules and Peptides 200020_178998
European Commission
SPACE4AMPS - Chemical Space for Antimicrobials on a Peptide Basis 885076