A cholesterol-lowering diet score correlates with serum LDL-cholesterol: Results from the DEDiCa trial

A cholesterol-lowering diet score, previously developped for epidemiological studies on seven dietary indicators, was tested to reflect serum cholesterol levels using data from DEDiCa clinical trial. Breast cancer patients with the highest adherence to the cholesterol-lowering diet reported lower LDL-cholesterol than those scarcely adherent (107 and 122 mg/dL, respectively; p=0.04). The difference was significant after adjustment for age, obesity, and physical activity. This provides support for the use of this score to identfy dietary patterns that reduce serum cholesterol levels.