Published January 1, 2027 | Version 1
Dataset Restricted

Human iPSC-derived microglia carrying LRRK2-G2019 mutation show Parkinson's disease related transcriptional profile and functions

Authors/Creators

  • 1. university of eastern finland

Description

This repository contains the data and the code used in Ohtone Sohvi's project.

A folder can contain the starting raw data in "data", the R scripts in order of execution (op1, op2 ..) and the "output" folder that contains the final processed data of each operation.

  • "PD_bulk_analysis" contains the processing and analysis of the bulk RNA sequencing data
  • "PD_bulk_fastq" contains the raw fastq sequences of the bulk RNA sequencing
  • "PD_bulk_nfcore" contains the results of processing the fasta sequences with nfcore rnaseq workflow 
  • "PD_scRNA_analysis" contains the analysis of the snRNA sequencing dataset
  • "PD_spatial" contains the raw data of the spatial sequencing, the assempbly of the spatial expression profiles starting from the DAPI images and the transcripts coordinates, the analysis performed on the data

Files

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The record is publicly accessible, but files are restricted to users with access.

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Only reviewers of the paper associated to the data and Malm's lab members can access to the data

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