Published July 22, 2022 | Version v.1
Journal article Open

Clinical Perspectives of Non-Coding RNA in Oral Inflammatory Diseases and Neuropathic Pain: A Narrative Review

  • 1. Department of Pharmacology in Dentistry, School of Dental Medicine, University of Belgrade, 11000 Belgrade, Serbia
  • 2. Department of Radiobiology and Molecular Genetics, Vinča Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia; Institute for Oncology and Radiology of Serbia, 11000 Belgrade, Serbia.

Description

Abstract. Non-coding RNAs (ncRNAs) represent a research hotspot by playing a key role in epigenetic and transcriptional regulation of diverse biological functions and due to their involvement in different diseases, including oral inflammatory diseases. Based on ncRNAs' suitability for salivary biomarkers and their involvement in neuropathic pain and tissue regeneration signaling pathways, the present narrative review aims to highlight the potential clinical applications of ncRNAs in oral inflammatory diseases, with an emphasis on salivary diagnostics, regenerative dentistry, and precision medicine for neuropathic orofacial pain.

 

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Clinical Perspectives of Non Coding RNA in Oral Inflammatory...ijms-23-08278.pdf

Additional details

Related works

Is documented by
35955417 (PMID)
Is identical to
PMC9368403 (pmcid)

Funding

Ministry of Education, Science and Technological Development
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200129 (University of Belgrade, Faculty of Dental Medicine) 200129